\u79c1\u305f\u3061\u306f\u7686\u3001\u81ea\u5206\u306e\u4f53\u306e\u4e2d\u306b\u3001\u76ae\u819a\u3084\u8840\u6db2\u306e\u3088\u3046\u306b\u3001\u3072\u3068\u3064\u3072\u3068\u3064\u306e\u7d30\u80de\u306e\u5bff\u547d\u304c\u77ed\u304f\u3001\u7d76\u3048\u305a\u5165\u308c\u66ff\u308f\u308a\u7d9a\u3051\u308b\u7d44\u7e54\u3092\u4fdd\u3064\u305f\u3081\u306b\u3001\u5931\u308f\u308c\u305f\u7d30\u80de\u3092\u518d\u3073\u751f\u307f\u51fa\u3057\u3066\u88dc\u5145\u3059\u308b\u80fd\u529b\u3092\u6301\u3063\u305f\u7d30\u80de\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u3053\u3046\u3057\u305f\u80fd\u529b\u3092\u6301\u3064\u7d30\u80de\u304c\u300c\u5e79\u7d30\u80de\u300d\u3067\u3059\u3002<\/p>\n

\u5e79\u7d30\u80de\u3068\u547c\u3070\u308c\u308b\u306b\u306f\u3001\u6b21\u306e\u4e8c\u3064\u306e\u80fd\u529b\u304c\u4e0d\u53ef\u6b20\u3067\u3059\u3002\u4e00\u3064\u306f\u5206\u5316\u80fd\u529b\u3068\u3044\u3063\u3066\u3001\u76ae\u819a\u3001\u8d64\u8840\u7403\u3001\u8840\u5c0f\u677f\u306a\u3069\u3001\u308f\u305f\u3057\u305f\u3061\u306e\u304b\u3089\u3060\u3092\u3064\u304f\u308b\u3055\u307e\u3056\u307e\u306a\u7d30\u80de\u3092\u4f5c\u308a\u51fa\u3059\u80fd\u529b\u3002<\/p>\n

\u3082\u3046\u4e00\u3064\u306f\u81ea\u5df1\u8907\u88fd\u80fd\u3067\u81ea\u5206\u3068\u307e\u3063\u305f\u304f\u540c\u3058\u80fd\u529b\u3092\u6301\u3063\u305f\u7d30\u80de\u306b\u5206\u88c2\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3068\u3044\u3046\u80fd\u529b\u3067\u3059\u3002<\/p>\n

<\/div>\n

\u3053\u3046\u3057\u305f\u300c\u5e79\u7d30\u80de\u300d\u306e\u6027\u8cea\u3092\u5229\u7528\u3057\u3066\u3001\u7d30\u80de\u305d\u306e\u3082\u306e\u3092\u85ac\u3068\u3057\u3066\u602a\u6211\u3084\u75c5\u6c17\u3092\u6cbb\u3059\u300c\u518d\u751f\u533b\u7642\u300d\u3068\u3044\u3046\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u306e\u7814\u7a76\u3084\u3001\u4f53\u5185\u306e\u7d30\u80de\u306e\u72b6\u614b\u3092\u304b\u3089\u3060\u306e\u5916\u3067\u518d\u73fe\u3057\u3066\u75c5\u6c17\u306e\u3057\u304f\u307f\u3092\u8abf\u3079\u308b\u7814\u7a76\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002<\/p>\n

\u5e79\u7d30\u80de\u4e0a\u6e05\u6db2(\u30b9\u30c6\u30e0\u30b5\u30c3\u30d7\uff09\u3068\u306f<\/h2>\n
$\"\"$ \u5e79\u7d30\u80de\u3092\u57f9\u990a\u3059\u308b\u3068\u304d\u306b\u3001\u5e79\u7d30\u80de\u304c\u5206\u6ccc\u3059\u308b\u6210\u5206\u306e\u3053\u3068<\/strong>\u3067\u3059\u3002<\/p>\n
\u3053\u306e\u6210\u5206\u306b\u306f\u3001500\u7a2e\u985e\u4ee5\u4e0a\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u6210\u5206\u304c\u542b\u307e\u308c\u3066\u304a\u308a\u3001\u305d\u3053\u306b\u306f\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u3068\u547c\u3070\u308c\u308b\u7d30\u80de\u6d3b\u6027\u306e\u30ab\u30ae\u3068\u306a\u308b\u60c5\u5831\u4f1d\u9054\u7269\u8cea\u304c\u8c4a\u5bcc\u306b\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306f\u3001\u4f53\u5185\u306e\u640d\u50b7\u3092\u53d7\u3051\u305f\u7d44\u7e54\u3084\u7d30\u80de\u306e\u6a5f\u80fd\u56de\u5fa9\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3001\u8001\u5316\u306a\u3069\u306b\u3088\u308a\u8870\u3048\u305f\u7d30\u80de\u306e\u56de\u5fa9\u3092\u5f8c\u62bc\u3057<\/strong>\u3059\u308b\u305f\u3081\u3001\u7f8e\u5bb9\u306b\u5bfe\u3059\u308b\u3055\u307e\u3056\u307e\u306a\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n

\u5e79\u7d30\u80de\u4e0a\u6e05\u6db2(\u30b9\u30c6\u30e0\u30b5\u30c3\u30d7\uff09\u306e\u6210\u5206<\/h2>\n
$\"\"$ \uff11\u3001IGF\u2010\uff11IGF-2\uff08Insulin-like growth factors\uff09<\/strong><\/p>\n
\u7b4b\u82bd\u7d30\u80de\u3001\u7b4b\u885b\u661f\u7d30\u80de\u306e\u5897\u6b96<\/p>\n
\u2192\u7b4b\u8089\u80a5\u5927\u3001\u9664\u8102\u80aa\u52b9\u679c\u3001\u6bdb\u9aea\u518d\u751f<\/p>\n
\uff12\u3001IGFBP\uff08insulin-like growth factor binding protein-3)<\/span><\/strong><\/p>\n
\u9aa8\u6210\u9577\u4fc3\u9032\u4f5c\u7528\u304c\u5f37\u3044<\/p>\n
\u2192\u9aa8\u5bc6\u5ea6\u306e\u5897\u52a0<\/p>\n
\uff13\u3001MCP-1\uff08Monocyte Chemotactic Protein-1\uff09<\/strong><\/p>\n
MCP-1\u306f\u3001in vitro\u306b\u3066\u3001\u5358\u7403\u306b\u5bfe\u3057\u8d70\u5316\u6027\u4ea2\u9032\u30fb\u6d3b\u6027\u9178\u7d20\u3084\u30ea\u30bd\u30be\u30fc\u30e0\u9175\u7d20\u306e\u7523\u751f\u653e\u51fa\u5897\u52a0\u3001\u3044\u304f\u3064\u304b\u306e\u816b\u760d\u306b\u5bfe\u3057\u3066\u5897\u6b96\u6291\u5236\u6d3b\u6027\u3092\u3082\u3061\u307e\u3059\u3002ES\/iPS\u7d30\u80de\u306e\u4e07\u80fd\u6027\u3092\u7dad\u6301\u3059\u308b\u6a5f\u80fd\u304c\u3042\u308b\u3053\u3068\u3082\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n
\u2192\u8001\u5316\u7269\u8cea\u9664\u53bb\u3001\u30b7\u30df\uff08\u904e\u5270\u30e1\u30e9\u30cb\u30f3\uff09\u9664\u53bb<\/p>\n
\uff14\u3001IL-4\uff08Interleukin-4\uff09<\/strong><\/p>\n
IL-4\u306f\u6297\u30a2\u30ec\u30eb\u30ae\u30fc\u4f5c\u7528\u3001\u6297\u611f\u67d3\u75c7\u3092\u793a\u3059\u4e8b\u304c\u77e5\u3089\u308c\u3066\u304a\u308a\u3001\u6c17\u7ba1\u652f\u5598\u606f\u306a\u3069\u306e\u75be\u60a3\u3092\u4e2d\u5fc3\u306b\u89e3\u6790\u304c\u884c\u308f\u308c\u3066\u3044\u308b\u3002<\/p>\n
\u2192\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u306e\u6291\u5236\u3001\u5275\u50b7\u6cbb\u7652\u306e\u4fc3\u9032<\/p>\n
\u5e79\u7d30\u80de\u4e0a\u6e05\u6db2(\u30b9\u30c6\u30e0\u30b5\u30c3\u30d7\uff09\u306f\u3069\u3093\u306a\u60a9\u307f\u306b\u30aa\u30b9\u30b9\u30e1\u304b\uff1f<\/h2>\n
$\"\"$ <\/p>\n
\u8cbb\u7528\uff1a\uff11\u672c\u300020,000\u5186\uff08\u7a0e\u629c\uff09\/\uff12\u672c\u4f7f\u7528\u300040,000\u5186\uff08\u7a0e\u629c\uff09<\/p>\n
10\u56de\u65bd\u8853\u3000400,000\u5186\uff08\u7a0e\u629c\uff09<\/p>\n
\u65bd\u8853\u6642\u9593\uff1a5\u5206<\/p>\n
\u30ea\u30b9\u30af\u30fb\u526f\u4f5c\u7528\uff1a\u65bd\u8853\u6642\u306e\u75db\u307f\u3001\u5185\u51fa\u8840\uff17\uff5e10\u65e5<\/p>\n
$\"\"$ <\/p>\n
\u8cbb\u7528\uff1a\uff11\u672c\u300020,000\u5186\uff08\u7a0e\u629c\uff09\/\uff12\u672c\u4f7f\u7528\u300040,000\u5186\uff08\u7a0e\u629c\uff09<\/p>\n
10\u56de\u65bd\u8853\u3000400,000\u5186\uff08\u7a0e\u629c\uff09<\/p>\n
\u65bd\u8853\u6642\u9593\uff1a10\u5206<\/p>\n
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<\/p>\n
\u7f8e\u5bb9\u90e8\u9580\u3067\u306f\u3001\u3001<\/strong><\/p>\n
\uff11\u3001\u518d\u751f\u52b9\u679c\u3092\u5229\u7528\u3057\u305f\u76ae\u819a\u306e\u82e5\u8fd4\u308a\u3001\u7f8e\u767d\u3001\u30af\u30de\u6cbb\u7642\u3001\u5c0f\u30b8\u30ef\u306e\u6539\u5584<\/p>\n
\uff12\u3001\u518d\u751f\u52b9\u679c\u3092\u5229\u7528\u3057\u305f\u6bdb\u9aea\u306e\u82e5\u8fd4\u308a\uff08\u5225\u540dHARG\u7642\u6cd5\uff09<\/p>\n
\uff13\u3001\u5275\u50b7\u6cbb\u7652\u306e\u4fc3\u9032\uff08\u30e1\u30b9\u3092\u4f7f\u3046\u624b\u8853\u3059\u3079\u3066\u3001\u79fb\u690d\u7247\u306e\u5b9a\u7740\u7387UP\uff09<\/p>\n
\u5065\u5eb7\u9762\u3067\u306f\u3001\u3001<\/b><\/p>\n
\u8001\u5316\u4e88\u9632\uff08\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\uff09<\/p>\n
\u5404\u7a2e\u75be\u60a3\u6539\u5584\uff08\u7cd6\u5c3f\u75c5\u3001\u52d5\u8108\u786c\u5316\u3001\u5404\u7a2e\u708e\u75c7\u75be\u60a3\u306e\u8efd\u6e1b\uff09<\/p>\n
\u6162\u6027\u75be\u60a3\u306e\u8efd\u6e1b\uff08\u795e\u7d4c\u6027\u75bc\u75db\u3001\u75fa\u308c\u3001\u8996\u529b\u56de\u5fa9\u3001\u6ecb\u990a\u5f37\u58ee\uff09<\/p>\n
\u306a\u3069\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n
\u5e79\u7d30\u80de\u4e0a\u6e05\u6db2(\u30b9\u30c6\u30e0\u30b5\u30c3\u30d7)\u306e\u7a2e\u985e<\/h2>\n
$\"\"$ \u79c1\u306e\u77e5\u308b\u9650\u308a\u3001\u9aa8\u9ac4\u7531\u6765\u3001\u8102\u80aa\u7531\u6765\u3001\u81cd\u5e2f\u8840\u7531\u6765\u306e3\u7a2e\u985e\u306b\u5e79\u7d30\u80de\u4e0a\u6e05\u6db2\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n
\u5f53\u9662\u3001\u63d0\u643a\u65bd\u8a2d\u306e\u682a\u5f0f\u4f1a\u793e\u30d0\u30a4\u30aa\u30bb\u30e9\u30d4\u30fc\u7814\u7a76\u6240\u306e\u5148\u751f\u65b9\u3068\u4f55\u5ea6\u304b\u4f1a\u98df\u3092\u3055\u305b\u3066\u9802\u304d\u8a73\u3057\u3044\u8a71\u3057\u3092\u805e\u304d\u307e\u3057\u305f\u3002<\/p>\n
3\u7a2e\u985e\u306e\u5e79\u7d30\u80de\u4e0a\u6e05\u6db2\u306e\u6709\u52b9\u6210\u5206\u3092\u8abf\u3079\u308b\u3068\u304b\u306a\u308a\u5dee\u304c\u3042\u308b\u305d\u3046\u3067\u3059\u3002<\/p>\n
\u3069\u308c\u304c\u512a\u308c\u3066\u3044\u308b\u3068\u8a00\u3046\u308f\u3051\u3067\u306a\u304f\u7528\u9014\u306b\u5408\u308f\u305b\u3066\u5909\u3048\u308b\u3068\u3044\u3046\u306e\u304c\u5927\u5207\u3060\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002<\/p>\n
\u6bdb\u9aea\u3001\u5275\u50b7\u6cbb\u7652\u306e\u4fc3\u9032\u2192\u8102\u80aa\u7531\u6765<\/p>\n
\u808c\u2192\u81cd\u5e2f\u8840\u7531\u6765<\/p>\n
\u306a\u3069\u306e\u3088\u3046\u306b\u3067\u3059\u3002<\/p>\n
\u5e79\u7d30\u80de\u4e0a\u6e05\u6db2\uff08\u30b9\u30c6\u30e0\u30b5\u30c3\u30d7\uff09\u306e\u5b89\u5168\u6027\u306b\u3064\u3044\u3066<\/h2>\n
$\"\"$ \u9759\u5ca1\u7f8e\u5bb9\u5916\u79d1 \u6a4b\u672c\u30af\u30ea\u30cb\u30c3\u30af\u3067\u306f\u30c9\u30ca\u30fc\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u306e\u5fb9\u5e95(\u611f\u67d3\u75c7\u306e\u6709\u7121)\u3001\u57f9\u990a\u6642\u306e\u52d5\u7269\u7531\u6765\u6210\u5206\u306e\u6392\u9664\u3001\u5b8c\u5168\u7121\u8840\u6e05\u57f9\u5730\u3092\u4f7f\u7528\u3057\u3001\u5e79\u7d30\u80de\u4e0a\u6e05\u6db2\u6cbb\u7642\u306e\u5b89\u5168\u6027\u3068\u5b89\u5b9a\u6027\u3092\u56f3\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n
\u5e79\u7d30\u80de\u4e0a\u6e05\u6db2\u306e\u4f7f\u7528\u65b9\u6cd5<\/h2>\n
$\"\"$ \u8001\u5316\u4e88\u9632\u3001\u4e88\u9632\u533b\u5b66\u3001\u6162\u6027\u75be\u60a3\u306e\u8efd\u6e1b\u2192\u9759\u8108\u6ce8\u5c04<\/p>\n
\u30a2\u30c8\u30d4\u30fc\u306a\u3069\u306e\u6c17\u306b\u306a\u308b\u7b87\u6240\u2192\u5857\u5e03<\/p>\n
\u9854\u3084\u9996\u3001\u30c7\u30b3\u30eb\u30c6\u3001\u624b\u306e\u7532\u3001\u982d\u76ae\u306a\u3069\u2192\u76ae\u4e0b\u6ce8\u5c04<\/p>\n
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\u4e9b\u7d30\u306a\u3053\u3068\u3067\u3082\u304a\u6c17\u8efd\u306b\u304a\u554f\u3044\u5408\u308f\u305b\u304f\u3060\u3055\u3044\u3002<\/p>\n
<\/p>\n
\u5f53\u9662HP\u306e\u5e79\u7d30\u80de\u4e0a\u6e05\u6db2\u8a3a\u7642\u5185\u5bb9\u306f\u3053\u3061\u3089\u3092\u30af\u30ea\u30c3\u30af<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"
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